Vancomycin hydrochloride CAS:1404-93-9 99% Keʻokeʻo a ʻeleʻele paha i ka pauka ʻulaʻula.
Helu Helu | XD90370 |
inoa mea kūʻai | ʻO Vancomycin hydrochloride |
CAS | 1404-93-9 |
ʻĀpana Molekala | C66H75Cl2N9O24.HCl |
Kaumaha Molecular | 1485.72 |
Nā kikoʻī mālama | 2 a 8 °C |
Kānāwai Kūʻai Kūlike | 29419000 |
Huahana Huahana
Wai | NMT 5.0% |
Nā metala kaumaha | NMT 30ppm |
pH | 2.5-4.5 |
ʻO nā endotoxins bacteria | NMT 0.33EU/mg o Vancomycin |
Akaka o ka Haʻina | Akaka |
Hoʻāʻo | 99% |
ʻO Vancomycin B | NLT 900ug/mg |
Ka palena o ka monodechlorovancomycin | NMT 4.7% |
Ka nana aku | Keʻokeʻo, aneane keʻokeʻo, a ʻeleʻele paha i ka pauka ʻulaʻula |
Ke piʻi nei ka piʻi ʻana o nā maʻi methicillin-resistant Staphylococcus aureus i loaʻa i ke kaiāulu i kahi wikiwiki weliweli.ʻO ka hoʻomaʻamaʻa maikaʻi ʻana i ka wā kahiko e pili ana i ka debridement mua a me ka hoʻokele antibiotic.Ua hoʻolālā ʻia kēia haʻawina no ka hoʻoholo ʻana i ka pono o ka empiric therapy i ka mālama ʻana i nā maʻi lima.Loaʻa nā maʻi me ka maʻi lima i ka vancomycin intravenous empiric i ke komo ʻana a i ʻole intravenous cefazolin.Ua nānā ʻia nā hopena me ka nui o ka maʻi, ka pane lapaʻau kūpono, a me ka lōʻihi o ka noho ʻana.Ua helu ʻia ke kumukūʻai me ka hoʻohana ʻana i ka huina kālā no kēlā me kēia maʻi ma nā hui ʻelua.Ua hana ʻia nā ʻikepili helu.He iwakāluakūmāhā i koho ʻia i ka cefazolin (52.2 pakeneka) a me 22 (47.8 pakeneka) i vancomycin.ʻAʻohe ʻokoʻa helu helu ma waena o ke kumukūʻai o ka mālama ʻana (p <0.20) a i ʻole ka lōʻihi o ka noho ʻana (p <0.18) ma waena o nā hui.ʻO nā maʻi i hoʻokaʻawale ʻia i ka cefazolin he kiʻekiʻe aʻe nā kumukūʻai o ka mālama ʻana ma mua o nā maʻi i hoʻokaʻawale ʻia i vancomycin (p <0.05).ʻO nā maʻi me nā maʻi koʻikoʻi ʻoi aku ka nui o ke kumu kūʻai o ka mālama ʻana (p <0.0001) a ʻoi aku ka lōʻihi o ka lōʻihi o ka noho ʻana (p = 0.0002).Ma kahi kokoke i ka pau ʻana o ke aʻo ʻana, ua ʻike ʻia he 72 pakeneka ka nui o ka loaʻa ʻana o ka methicillin-resistant S. aureus i loaʻa i ke kaiāulu ma ka halemai kalana o nā mea kākau, ʻo ia ka mea i hoʻopau mua ʻia ke aʻo ʻana e ka papa loiloi ʻoihana no ka nui o ka nui. ʻAʻole i hoʻokumu paʻa ʻia ka mālama mua ʻana no ka S. aureus kūʻē i ka methicillin.ʻAʻole ʻokoʻa ka hopena i ka hoʻohana ʻana i ka cefazolin versus vancomycin ma ke ʻano he mea hana mua i ʻike ʻia.