Spectinomycin dihydrochloride pentahydrate CAS:22189-32-8 Ka pauka kristal keokeo
| Helu Helu | XD90369 |
| inoa mea kūʻai | Spectinomycin dihydrochloride pentahydrate |
| CAS | 22189-32-8 |
| ʻĀpana Molekala | C14H24N2O7·2HCl·5H2O |
| Kaumaha Molecular | 495.30 |
| Nā kikoʻī mālama | 2 a 8 °C |
| Kānāwai Kūʻai Kūlike | 29419090 |
Huahana Huahana
| Hoʻāʻo | 99% |
| Ka nana aku | ʻO ka pauka kristal keʻokeʻo |
No ka noiʻi ʻana i ka epidemiology molecular o nā mea hoʻokaʻawale o Neisseria gonorrhoeae mai Saskatchewan, Kanada, me ka hoʻohana ʻana i ka Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), a e loiloi i nā hui ma waena o ka antimicrobial susceptibility (AMS) a me nā ʻano strain kikoʻī (STs). , i hōʻiliʻili ʻia ma waena o 2003 a me 2008, ua paʻi ʻia e NG-MAST.Ua hui pū ʻia nā ST inā he maʻamau kekahi o kā lākou alleles a ʻokoʻa kekahi e ≤1% ma ke kaʻina DNA.Ua hoʻoholo ʻia ka AMS e ka dilution agar (CLSI) i ʻehiku mau lāʻau. /320) o nā kaʻawale.N gonorrhoeae hoʻokaʻawale maʻalahi i nā lāʻau antimicrobial i ho'āʻo nui ʻia (p<0.05) pili me ST 25 (87%).ʻO nā hui koʻikoʻi ʻē aʻe ma waena o ST a me AMS e komo pū ana: ST 3654 a me nā mea hoʻokaʻawale me nā haʻahaʻa haʻahaʻa haʻahaʻa o ≥0.03 mg / L i ke kolu o ka hanauna ceph alosporins;ST 3711 (100%) a me TRNG;a me ST/group 3654 (43%) a me ke kū'ē chromosomal i ka penicillin a me ka tetracycline.Nui nā NG-MAST STs/pūʻulu i pili nui me nā kaʻawale me ke kū'ē chromosomal i ka tetracycline.ʻO nā mea hoʻokaʻawale kūʻē i ka ciprofloxacin (n=5) a me ka azithromycin (n=2) i ʻike ʻia ma ke ʻano he ST pākahi.Uaʻikeʻia nā hui nui ma waena o kēlā me kēia ST, ke kāne a me ka makahiki o ka mea maʻi, a me ka māhele'āina a me ke kino.Ma muli o ka ʻokoʻa ʻana o nā ST ma nā ʻāina like ʻole, pono ka hoʻohana ʻana o NG-MAST no ka wānana o AMS ma ke ao holoʻokoʻa.
