Doxycycline hyclate CAS:24390-14-5 99% ʻO ka pauka crystalline melemele
| Helu Helu | XD90368 |
| inoa mea kūʻai | Doxycycline hyclate |
| CAS | 24390-14-5 |
| ʻĀpana Molekala | C22H24N2O8·HCl·0.5C2H6O·0.5H2O |
| Kaumaha Molecular | 512.94 |
| Nā kikoʻī mālama | 2 a 8 °C |
| Kānāwai Kūʻai Kūlike | 29413000 |
Huahana Huahana
| haumia A | <2% |
| haumiaB | <2% |
| Kahuli kiko'ī | -105 a i -120 |
| pH | 2-3 |
| haumia C | <0.5% |
| haumiaD | <0.5% |
| Nalo ma ka maloo | 1.4-2.8% |
| Hoʻāʻo | 99% |
| Koena ma ka Ignition | <0.4% |
| Ka hoʻopaʻa ʻana | 300-335 |
| ʻO nā mea haumia ʻē aʻe | <0.5% |
| Ka nana aku | Ka pauda kristal melemele |
| haumia F | <0.5% |
| haumiaE | <0.5% |
| Ethyl Alcohol | 4.5 - 6% |
| Absorbency o ka haumia | <0.07% |
ʻO ka hoʻokumu ʻana o ka biofilm ma ka abutment niho hiki ke alakaʻi i ka mucositis peri-implant a me ka peri-implantitis ma hope.Hoʻomaʻamaʻa ʻia kēia mau hihia me nā lāʻau lapaʻau e like me doxycycline (Doxy).Ma ʻaneʻi ua hoʻohana mākou i ke ʻano electrochemical o ka cathodic polarization e kāhiko iā Doxy ma ka ʻili o waho o kahi mea hoʻopili niho.Ua hōʻike ka ʻili i uhi ʻia ʻo Doxy i ka hoʻokuʻu ʻia ʻana o ka paʻakai phosphate-buffered i ka hola 24 mua.Eia nō naʻe, ua mau ka nui o Doxy ma luna o ka ʻili no ka liʻiliʻi o 2 mau pule ma kahi laʻana 5 mA-3 h me ka nui Doxy kiʻekiʻe, e hōʻike ana i kahi hiki bacteriostatic mua a lōʻihi o ka ʻili i uhi ʻia.Ua kālailai ʻia ke kemika ʻili e ka x-ray photoelectron spectroscopy a me ka lua o ka ion mass spectrometry.Ua loiloi ʻia ka ʻili o ka ʻili e ka microscopy electron emission scanning a me ka profilometry blue-light.ʻOi aku ka lōʻihi o ka manawa polarization mai 1 h a hiki i 5 h a ʻoi aku ke kiʻekiʻe o kēia manawa mai 1 a 15 mA cm(-2) i hopena i ka nui o Doxy ma ka ʻili.Ua uhi ʻia ka ʻili e kahi papa o Doxy ma lalo o 100 nm me ka ʻole o nā loli nui i ka topography.Ua kālailai ʻia ka waiwai antibacterial o ka ʻili i uhi ʻia e Doxy e ka biofilm a me ka hoʻonui ʻana i ka planktonic assays me Staphylococcus epidermidis.ʻO nā laʻana i uhi ʻia ʻo Doxy i hōʻemi i ka hōʻiliʻili biofilm a me ka ulu ʻana o ka planktonic i ka moʻomeheu broth, a ua kāohi pū i ka ulu ʻana o ka bacteria ma nā papa agar.ʻOi aku ka ikaika o ka hopena antibacterial no nā laʻana o 5 mA-3 h i uhi ʻia me ka nui o Doxy i hoʻohālikelike ʻia me ka 1 mA-1 h.No laila, hiki i kahi abutment i uhi ʻia me Doxy ke hiki ke pale i ka colonization bacteria ke ʻike ʻia i ka lua waha.Hiki i ka Doxy-coating ke ala kūpono e hoʻomalu ai i ka mucositis peri-implant a pale i kona piʻi ʻana i peri-implantitis.
