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1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine -3-carboxylic acid ethyl ester he hui kemika paʻakikī i hōʻike i ka hiki i nā wahi like ʻole o ka lāʻau kemika a me ka ʻike ʻana i ka lāʻau.Eia ka wehewehe ʻana o kāna hoʻohana ʻana ma kahi o nā huaʻōlelo 300. ʻO kēia pūhui, i kapa pinepine ʻia ʻo ka ethyl ester derivative o 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl) phenyl] -4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] pyridine-3-carboxylic acid, no ka papa o ka pyrazolo [3,4-c] pyridine derivatives.ʻO kēia mau derivatives ua hoʻohuli i ka manaʻo i ka ʻike ʻana i ka lāʻau ma muli o ko lākou hiki i nā wahi lapaʻau like ʻole.Ua hōʻike ʻo Pyrazolo [3,4-c] pyridine derivatives i ka hana anti-proliferative e kūʻē i kekahi mau ʻano o nā maʻi maʻi maʻi.ʻO ko lākou hiki ke kāohi i nā ala kikoʻī e pili ana i ka ulu ʻana a me ke ola ʻana e lilo lākou i mau moho no ka hoʻomohala ʻana i nā lāʻau anti-cancer.Pono nā haʻawina hou aʻe e ʻimi ai i ke ʻano o ka hana a loiloi i ka pono o ka pūhui i nā preclinical a me nā hoʻonohonoho lāʻau lapaʻau.Ua hōʻike ʻo ia i ka hana e kūʻē i nā maʻi bacteria like ʻole, me nā maʻi Gram-positive a me Gram-negative bacteria.ʻO ka hiki ke hoʻopaʻa i nā maʻi he nui e hōʻike ana i kona hiki ke hoʻopaʻapaʻa i ka maʻi bacteria kūʻē i ka lāʻau, ua lilo ia i mea hopohopo olakino koʻikoʻi.Pono ka noiʻi hou aʻe e noiʻi i kāna ʻano hana a nānā i kona pono i ka hakakā ʻana i nā maʻi bacterial.He kuleana koʻikoʻi ka ʻāʻī ma nā ʻano like ʻole e like me ka rheumatoid arthritis a me psoriasis.Ua hōʻike kēia mau derivatives i nā waiwai anti-inflammatory ma ka hoʻololi ʻana i nā ala kikoʻī e pili ana i ka pane inflammatory.Hōʻike kēia i ko lākou hiki ke lilo i mau lāʻau lapaʻau no ka mālama ʻana i ka ʻeha mau a me nā maʻi pili.Ua noiʻi ʻia no kona hiki ke loaʻa i nā maʻi neurological e like me ka maʻi Alzheimer a me ka maʻi Parkinson.Hiki i ka hui ke hoʻololi i nā mea loaʻa a me nā enzyme i pili i ka holomua o ka maʻi, hiki ke hāʻawi i nā hopena neuroprotective.Eia nō naʻe, pono ka noiʻi hou ʻana e hoʻomaopopo pono i kāna hana o ka hana a nānā i kona pono i ka mālama ʻana i kēia mau maʻi paʻakikī. yl) phenyl] -4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] pyridine-3-carboxylic acid ethyl ester paʻa i ka ʻōlelo hoʻohiki ma nā wahi therapeutic, me ka anti-cancer, antibacterial, anti-inflammatory. , a me nā pilikia CNS.Aia kona hiki i kona hiki ke kuhikuhi i nā ala kikoʻī a me nā mea loaʻa i komo i kēia mau kūlana.Eia nō naʻe, pono ka noiʻi hou a me ka noiʻi ʻana e ʻimi piha i kona hiki, e hoʻopaʻa pono i kāna mau waiwai, a loiloi i kona palekana a me ka pono i nā hoʻonohonoho lapaʻau.