Nā huahana

ʻO Clopidogrel camphorsulfonate kahi hui lāʻau lapaʻau me ke ʻano kemika C16H16ClNO2S·C10H16O4S.ʻIke pinepine ʻia ʻo Clopidogrel S-oxide camphorsulfonate a i ʻole Clopidogrel CAMS.ʻO kēia pūhui he chiral derivative o clopidogrel, kahi lāʻau antiplatelet i hoʻohana nui ʻia.Hana ia ma ke kāohi ʻana i ka platelet aggregation, pale i ka hoʻokumu ʻana o ke koko, a me ka hōʻemi ʻana i ka hopena o nā hanana cardiovascular.Hoʻopili pono ka pūhui i ka mea loaʻa P2Y12 ma nā platelets, a laila ke kāohi ʻana i ke kaʻina hana hoʻāla a me ka pale ʻana i ka platelet aggregation.ʻO kēia kaʻina hana e hana maikaʻi ai ʻo Clopidogrel camphorsulfonate i ka pale ʻana i ka thrombosis arterial a me ka hoʻohaʻahaʻa ʻana i ka hopena o nā hanana cardiovascular adverse, me ka puʻuwai puʻuwai a me nā hahau.I ka manawa e ʻai ʻia ai, hoʻololi ʻia ka metabolic i loko o ke akepaʻa, ka hopena i ka hoʻokumu ʻana o ka metabolite ikaika.A laila hoʻopaʻa ʻole kēia metabolite ikaika i ka receptor P2Y12, e hoʻohana ana i kāna mau hopena antiplatelet no kahi manawa lōʻihi.He lōʻihi ka lōʻihi o ka hana ʻana o ka pūhui, e koi ana i hoʻokahi dosing i kēlā me kēia lā i ka hapa nui o nā hihia. intervention (PCI) me ka hoʻokomo stent.Hoʻohana nui ʻia ia e pale i ka hiki ʻana o nā hanana thrombotic i nā maʻi me ka mōʻaukala o ka hahau a i ʻole ka maʻi ʻaʻaʻa peripheral.Hoʻohana pinepine ʻia ka hoʻohana ʻana o Clopidogrel camphorsulfonate me ka aspirin haʻahaʻa haʻahaʻa e hoʻomaikaʻi i ka lāʻau antiplatelet. heluna kanaka maʻi.Hiki ke ʻokoʻa ke ʻano a me ka lōʻihi o ka mālama ʻana ma muli o ke kūlana olakino o kēlā me kēia kanaka, a pono paha ka nānā mau ʻana i ka hana platelet a me nā hoʻāʻo koko e hōʻoia i ka hopena therapeutic maikaʻi loa. ʻo nā mea e pili ana i ka thrombosis arterial.ʻO kāna mau waiwai antiplatelet a me ke kāohi koho ʻana i ka mea hoʻokipa P2Y12 e lilo ia i lāʻau lapaʻau maikaʻi no ka hōʻemi ʻana i ka hopena o nā hanana cardiovascular ʻino.Eia nō naʻe, e like me kekahi hui lāʻau lapaʻau, pono e mālama ʻia i ka hoʻohana ʻana, a pono nā mea maʻi e mālama i nā ʻōlelo aʻoaʻo a me ke alakaʻi ʻana o kā lākou mea mālama ola.