Nā huahana

Ua hoʻomohala ʻia nā kiʻiʻoniʻoni Mucoadhesive i loaʻa nā nanoparticles i hoʻouka ʻia e curcumin, me ka manaʻo e hoʻolōʻihi i ka manawa noho o ke ʻano hana i loko o ka lua waha a hoʻonui i ka lawe ʻana i ka lāʻau ma o ka mucosa buccal.Ua hoʻomākaukau ʻia nā kiʻiʻoniʻoni ma ke ʻano hoʻolei ʻana ma hope o ka hoʻokomo ʻia ʻana o ka curcumin-loaded chitosan-coated polycaprolactone nanoparticles i loko o ka plasticized chitosan solutions.Ua hoʻohana ʻia nā ʻāpana molar like ʻole o ka mucoadhesive polysaccharide chitosan a me nā ʻano o ka plasticizer glycerol e hoʻomaikaʻi i nā kūlana hoʻomākaukau.ʻO nā kiʻiʻoniʻoni i loaʻa ma ka hoʻohana ʻana i ka chitosan nui a me ka molar kiʻekiʻe i ʻike ʻia he homogeneous a maʻalahi.Ua māhele like ʻia nā nanoparticles i hoʻokomo ʻia i ka Curcumin ma ka ʻili kiʻiʻoniʻoni, e like me ka mea i ʻike ʻia e ka microscopy atomic ikaika a me nā kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi.Hōʻike ka ʻike ʻana i nā ʻāpana keʻa kiʻiʻoniʻoni me ka hoʻohana ʻana i ka FEG-SEM i ke ʻano o nā nanoparticles i loko o nā kiʻiʻoniʻoni.Eia kekahi, ua hōʻike ʻia nā kiʻiʻoniʻoni i ka maikaʻi o ka hydration i ka hoʻonā ʻana i ka saliva i hoʻohālikelike ʻia, e hōʻike ana i ka pehu kiʻekiʻe ma kahi o 80% a me ka lawe ʻana i ka curcumin i loko o ka vitro.Hōʻike kēia mau hopena i nā kiʻiʻoniʻoni mucoadhesive i loaʻa nā nanoparticles e hāʻawi i kahi ala hoʻohiki no ka hāʻawi ʻana i ka curcumin buccal, he mea pono paha i ka mālama ʻana i nā maʻi periodontal e koi ai i ka hāʻawi ʻana i ka lāʻau lapaʻau mau.© 2014 Wiley Periodicals, Inc.