Nā huahana

ʻO ka maikaʻi a me ka palekana o ka tafluprost 0.0015% a me ka timolol maleate 0.5% hoʻohui paʻa i nā maʻi me ka hypertension ocular a i ʻole glaucoma open-angle.

ʻO ka hoʻohaʻahaʻa ʻana i ke kaomi intraocular (IOP) i kēia manawa ʻo ke ala lapaʻau wale nō i ka mālama ʻana i ka glaucoma i hōʻoia ʻia i ka holomua.Pono ke koho ʻana i ka lāʻau lapaʻau e noʻonoʻo i ka pono, ka hoʻomanawanui, ka palekana, ka maikaʻi o ke ola, ka pili ʻana a me ke kumukūʻai.ʻAʻole hiki i ka monotherapy ke hōʻemi i ka IOP maikaʻi ma 40 - 75% o nā maʻi glaucoma ma hope o 2 mau makahiki o ka lāʻau lapaʻau.I kēia manawa, loaʻa ʻekolu prostaglandin / timolol maleate 0.5% hui paʻa (FCs). Hāʻawi kēia loiloi i kahi ʻike e pili ana i ka tafluprost-timolol FC (TTFC, Santen Oy) a me kāna mau pūhui pākahi.Hōʻuluʻulu ʻo ia i ka ʻikepili e pili ana i ka pono a me ka palekana, me ka ʻikepili hoʻohālikelike me ka prostaglandin/timolol FC i loaʻa.Eia nō naʻe, ʻoi aku ka maikaʻi o kāna ʻano hopena maikaʻi ʻole i ka poʻe maʻi e pili ana i nā preservatives.ʻAʻohe mana kūʻai o ka TTFC me ka mālama ʻole.Hoʻokahi wale nō hoʻokolohua Phase III i paʻi ʻia a hiki i kēia manawa, akā ke hoʻohiki nei nā hopena ma ke ʻano o ka pono, ka ʻae a me ka palekana.He kuleana ko ka TTFC i ka mālama ʻana i ka glaucoma open-angle a me ka hypertension ocular.