Hoechst 33258 Cas: 23491-45-4 Pale melemele crystalline pauka
Helu Helu | XD90536 |
inoa mea kūʻai | Hoechst 33258 |
CAS | 23491-45-4 |
ʻĀpana Molekala | C25H24N6O·3(HCl) |
Kaumaha Molecular | 533.88 |
Nā kikoʻī mālama | -15 a -20 °C |
Kānāwai Kūʻai Kūlike | 32129000 |
Huahana Huahana
Ka nana aku | Ka pauda kristal melemele melemele |
Hoʻāʻo | 99% |
Ua aʻo ʻia ka pilina ma waena o ka lāʻau antidiabetic, Metformin a me ka pipi thymus DNA (CT-DNA) ma (50mM Tris-HCl) buffer e ka UV-Visible absorption, fluorescence, CD spectroscopy a me nā ana viscosity.Ma nā haʻawina fluorimetric, ua hōʻike ka enthalpy a me ka entropy o ka hopena ma waena o ka lāʻau lapaʻau a me CT-DNA he exothermic ka hopena (ΔH=-35.4522 kJ mol(-1); ΔS=-49.9523 J mol(-1)K(-1 )).Ua hōʻike ʻia nā haʻawina hoʻokūkū hoʻokūkū e hiki i ka lāʻau lapaʻau ke hoʻokuʻu loa iā Hoechst 33258.Ua hōʻike ka paʻakikī i ka hyperchromism absorption i kāna spectrum UV-Vis me DNA.ʻO ka hoʻopaʻa mau ʻana i helu ʻia, K(b), i loaʻa mai nā haʻawina absorption UV-Vis ʻo 8.3×10(4)M(-1).Eia kekahi, ʻo ka hoʻololi ʻana i ka spectra CD i mua o ka lāʻau lapaʻau e hōʻike ana i ka stabilization o ka ʻano B lima ʻākau o CT-DNA.ʻO ka hope, ua hōʻike ʻia nā ana viscosity e hiki ke hoʻopaʻa ʻia ka paʻa ʻana o ka paʻakikī me CT-DNA, ma muli o ka hoʻopaʻa ʻana.