Nicotinamide Cas: 98-92-0 ʻO ka pauka keʻokeʻo
| Helu Helu | XD90447 |
| inoa mea kūʻai | Nicotinamide |
| CAS | 98-92-0 |
| ʻĀpana Molekala | C6H6N2O |
| Kaumaha Molecular | 122.12 |
| Nā kikoʻī mālama | Ambient |
| Kānāwai Kūʻai Kūlike | 29362900 |
Huahana Huahana
| Ka nana aku | Pauda keʻokeʻo |
| Hoʻāʻo | 99% |
| Nā metala kaumaha | 128°C ~ 131°C |
| ʻIkepili | maikaʻi |
| pH | 6.0 ~ 7.5 |
| Nalo ma ka maloo | ≤0.5% |
| Ka hikiwawe | Kūlike |
| Lehu Sulphated | ≤0.1% |
| Akaka o ka Haʻina | Akaka |
| Metala Kaumaha | ≤0.003% |
Ua hoʻokumu mua mākou i ka moʻomeheu lōʻihi, 3-dimensional o nā organoids mai nā ʻiole ʻiole (ka ʻōpū, ka ʻōpū, ka pancreas, a me ka ate) a me ka ʻōpū o ke kanaka a me ka pancreas.Ma ʻaneʻi, wehewehe mākou i nā kūlana e pono ai no ka moʻomeheu 3-dimensional lōʻihi o nā pūnaewele ʻōpū o ke kanaka.Hiki ke hoʻohana ʻia ka ʻenehana no ke aʻo ʻana i ka pane epithelial i ka maʻi me Helicobacter pylori. Ua hana mākou i nā organoids mai nā laʻana o ka ʻōpū o ke kino kanaka.Hoʻokumu ʻia nā kūlana moʻomeheu ma muli o nā mea no ka ʻōpū o ka ʻiole a me nā ʻōnaehana ʻōpū kanaka.Ua hoʻohana mākou i ka microinjection e hoʻopili i nā organoids me H pylori.Ua ana ʻia nā pane epithelial me ka hoʻohana ʻana i ka microarray a me ka quantitative polymerase chain reaction analysis.Hoʻomoʻa mākou i nā pūnaewele mai nā ʻiʻo ʻōpū olakino, nā pūnaewele i hoʻokaʻawale ʻia hoʻokahi, a i ʻole nā ʻiʻo tumora.Ua mālama nā Organoids i nā hiʻohiʻona he nui o kā lākou mau kiko ma muli o kā lākou mōʻaukala, hōʻike o nā māka, a me ka euploidy.ʻO nā organoids mai ka ʻiʻo olakino i hōʻike i nā hōʻailona o 4 laina o ka ʻōpū a hoʻonohonoho ponoʻī ʻia i loko o nā kikowaena a me nā lua.Hiki ke kuhikuhi ʻia lākou e hōʻike kikoʻī i nā laina o ka ʻōpū ʻōpū, a i ʻole ka lua ʻōpū, ma ka hoʻohui ʻana i ka nicotinamide a me ka wehe ʻana o WNT.ʻOiai ʻo nā laina laina o ka lua ʻōpū i loaʻa wale nā hopena liʻiliʻi i ka maʻi maʻi bacteria, ua kau nā laina laina o ka ʻōpū i kahi pane inflammatory ikaika.Hiki ke hoʻohana ʻia kēia ʻōnaehana no ke aʻo ʻana i ka maʻi H pylori a me nā maʻi ʻeha ʻē aʻe. Kuleana kope © 2015 AGA Institute.Paʻi ʻia e Elsevier Inc. Ua mālama ʻia nā kuleana āpau.
