o-Cresolphthalein Complexone CAS: 2411-89-4 Pauka keʻokeʻo
| Helu Helu | XD90463 |
| inoa mea kūʻai | o-Cresolphthalein Complexone |
| CAS | 2411-89-4 |
| ʻĀpana Molekala | C32H32N2O12 |
| Kaumaha Molecular | 636.62 |
| Nā kikoʻī mālama | Ambient |
| Kānāwai Kūʻai Kūlike | 2932209090 |
Huahana Huahana
| Nalo ma ka maloo | 7.23% |
| Ka nana aku | Pauda keʻokeʻo |
| Hoʻāʻo | 99% |
| Ka Mahana Waihona | +20 ° C |
| Kaumaha Molecular | 636.6 |
| Ka hikiwawe | Haʻina poni akaka |
| Koena ma ka Ignition | 0.5% ka nui |
| Nitrogen | 4.1-4.7% |
| Lambda max | 573nm i ka 0.1N sodium hydroxide |
| Lamda Max | 575(377)nm i ka 0.1 N sodium hydroxide |
| Kalapona | 58-63% |
ʻO nā protein morphogenetic iwi (BMPs) ke kuleana nui i ka hoʻokumu ʻana o ka iwi a me ka cartilage.No kēia mau waiwai, hoʻohana ʻia nā BMP ma ke kahua o ka ʻenekinia kiko e hoʻoulu ai i ka hoʻōla hou ʻana o ka iwi i nā ʻiʻo i hōʻino ʻia.No ka lanakila ʻana i nā drawbacks ma muli o ka hoʻohana ʻana i nā protein holoʻokoʻa, ua puka mai nā peptides synthetic i loaʻa mai ko lākou mau makua BMP ma ke ʻano he molekala hoʻohiki no ka hoʻolālā biomaterial.Ma ke kahua o ka hoʻokolohua BMP-2 receptor complexes i hōʻike ʻia i loko o ka palapala, ua hoʻolālā mākou i ʻekolu peptides, e hana hou ana i ka ʻāina BMP-2 i kuleana no ka hoʻopaʻa ʻana i ke ʻano II receptor, ActRIIB.Hōʻike ʻia kēia mau peptides e ka NMR, a ua hōʻike ʻia nā hiʻohiʻona o ka peptide-receptor binding interface e nā hoʻokolohua docking.Hoʻopili ʻia nā pilina pili peptide-receptor e ka ELISA a me nā ʻenehana resonance plasmon surface.Eia kekahi, ua hana ʻia nā hoʻokolohua cellular e loiloi i kā lākou waiwai osteoinductive.ʻO kahi peptide chimera, i loaʻa ma ka hoʻohui ʻana i ka sequence port ions 73-92 a me 30-34 o BMP-2, e hōʻike ana i ka pilina maikaʻi loa no ActRIIB i ka moʻo a hōʻike i kahi hoʻomaka maikaʻi no ka hoʻolālā ʻana i nā pūhui hou hiki ke hana hou i nā waiwai osteogenic o ka makua BMP-2.
