Nā huahana

ʻO ka Galactosidase e pili ana i kahi papa o nā enzyme e hoʻoheheʻe i nā mea i loaʻa nā mea paʻa galactosidic, e like me ka lactose (ʻo ka lactose he disaccharide i hana ʻia e ka condensation dehydration o hoʻokahi mole o ka glucose a me hoʻokahi mole o ka galactose).Hoʻokaʻawale nui ʻia i α-galactosidase a me β-galactosidase.Hoʻopili ʻo α-Galactosidase i ka hydrolysis o nā paʻa α-galactosidase, hiki ke hoʻololi a hoʻoheheʻe i nā mea anti-nutritional α-galactosides i ka meaʻai a me ka soy meaʻai, a hoʻomaikaʻi i kā lākou meaʻai.Eia kekahi, ua loaʻa i ka enzyme kekahi mau noi i ka lāʻau lapaʻau, ka hana mānoanoa a me nā ʻoihana pepa.ʻAʻole hoʻohana nui ʻia ka β-Galactosidase i ka ʻoihana meaʻai, akā hoʻokani pū kekahi i kahi hana koʻikoʻi ma nā kahua o ka biotechnology e like me genetic engineering, enzyme engineering, protein engineering, etc., a ua hoʻomaka e hoʻohana nui ʻia i ka lāʻau lapaʻau. a me nā kula ʻē aʻe.

ʻO ka α-galactosidase (α-galactosidase, α-gal, EC 3.2.1.22) he exoglycosidase e hoʻokahe i ka hydrolysis o nā paʻa α-galactosidic, a ua kapa ʻia hoʻi ʻo ia melibiase no ka mea hiki iā ia ke decompose melibiose , nāna e hoʻoheheʻe i ka hydrolysis o α-galactosidic. paa paa.Hoʻohana kēia hiʻohiʻona no ka hoʻomaikaʻi ʻana a me ka hoʻopau ʻana i nā anti-nutrients i ka hānai a me nā meaʻai soy.Eia kekahi, hiki iā ia ke hoʻomaopopo i ka hoʻololi ʻana o ka hui koko B→O i ka lāʻau lapaʻau, hoʻomākaukau i ke ʻano o ke koko āpau, a pāʻani pū kekahi i kahi hana koʻikoʻi i ka enzyme replacement therapy o Fabry maʻi.Hiki i ka Alpha-galactosidase ke hana ma luna o nā polysaccharides paʻakikī, glycoproteins a me nā sphingolipid i loaʻa nā paʻa alpha-galactosidic.Loaʻa i kekahi mau enzyme α-galactosidase ka hopena o ka transgalactosylation i ka wā e hoʻonui nui ʻia ka substrate concentration, hiki ke hoʻohana ʻia no ka synthesis o oligosaccharides a me ka hoʻomākaukau ʻana i nā derivatives cyclodextrin.ʻO ka hoʻomohala ʻana o ka neutrophilic a i ʻole pH-stable α-galactosidase a me ka ʻimi ʻana i nā microorganism a i ʻole nā ​​​​mea kanu me ka hana enzyme kiʻekiʻe i lilo i wahi wela noiʻi i nā makahiki i hala.He nui ka thermostable α-galactosidases i lohi iki i ka makemake nui o ka poe epekema ma muli o ko lakou mau waiwai kūikawā, me ka manaʻo e hoʻohana i ko lākou thermostability e pāʻani i ka hana ʻoi aku ka nui ma nā ʻoihana ʻenehana, a me ka hōʻike ʻana i ka hoʻohana ākea ma nā kahua o ka ʻepekema a me ka ʻenehana a me ka lāʻau lapaʻau.nā manaʻo noi.