Nā huahana

ʻO Vancomycin hydrochloride kahi lāʻau antibiotic glycopeptide a ʻo ia ka paʻakai hydrochloride o vancomycin.He keʻokeʻo a keʻokeʻo-like crystalline pauda i ka lumi wela.ʻO kāna hana o ka hana, hiki iā ia ke hoʻopaʻa me ka pilina kiʻekiʻe i ka poly-terminus alanyl-alanine o ka peptide precursor i loaʻa ma ka paia o ka cell i nā cell bacteria sensitive, e ālai ana i ka biosynthesis o ka peptide glycan polymer constituting the bacterial cell wall, a pēlā. ka hopena i nā hemahema o ka paia cell a pepehi hou i ka bacteria.Eia kekahi, hiki ke hoʻololi i ka permeability o ka membrane cell bacteria, a koho koho i ka synthesis o RNA.ʻO ka hiʻohiʻona o vancomycin hydrochloride kona hopena bactericidal ikaika e kū'ē i nā bacteria Gram-positive e like me Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, a me streptococcus pneumoniae.Loaʻa iā ia kekahi mau hopena anti-bacteria ma Streptococci anaerobius, Clostridium difficile, Bacillus anthracis, Actinomycetes, Corynebacterium diphtheria, Neisseria gonorrhoeae, Streptococcus viridans, Streptococcus bovis, a me Streptococcus faecalis.Eia nō naʻe, no ka hapa nui o nā maʻi bacteria Gram-negative, Mycobacterium, Rickettsia genus, Chlamydia a i ʻole fungi, ʻaʻole ia.Hoʻohana ʻia ia i ka mālama ʻana i ka maʻi i hoʻokumu ʻia e ka methicillin-resistant Staphylococcus aureus a me nā mea maʻi ʻē aʻe: sepsis, endocarditis, osteomyelitis, arthritis, ʻeha ʻeha, ʻeha ʻokiʻoki a me nā maʻi ʻē aʻe o ke kula kiʻekiʻe, pneumonia, lung abscess, empyema, peritonitis, maningitis, pseudomembranous colitis, a me nā maʻi ʻili a me nā ʻiʻo palupalu.ʻO ia ke koho mua no nā poʻe maʻi maʻi i ka penicillin a loaʻa i ka endocarditis enterococcal a me Corynebacterium (class diphtheria sp) endocarditis.