Nā huahana

Hoʻāʻo pinepine ʻia ka globulin helu ʻia (ka nui o ka protein - albumin) ma ke ʻano he ʻāpana o ka ʻaoʻao hoʻāʻo hana o ke akepaʻa ma ka mālama mua a me ke kula kiʻekiʻe a hoʻoholo i ka ʻike o ka serum globulin, nona ka immunoglobulins he mea nui.ʻO ka hoʻohana nui ʻana o ka globulin helu ʻia ʻo ia ka ʻike ʻana i nā paraproteins ke kiʻekiʻe ka pae.Ua noiʻi kēia noiʻi i ka hiki ke hoʻohana i nā pae haʻahaʻa o ka globulin helu ʻia e ʻike i ka hemahema o ka antibody.Ua hōʻiliʻili ʻia nā laʻana serum me ka ʻoki ʻana o ka globulin helu <18 g/l ma muli o nā hopena o kahi noiʻi pailaka mai ʻeiwa mau haukapila ma Wales ma kahi o 12 mau mahina.Ua loaʻa ka ʻike noi inoa ʻole a ua hoʻāʻo ʻia nā laʻana no nā pae immunoglobulin, electrophoresis serum a, inā kūpono, immunofixation.Ua hana ʻia kahi ʻano hoʻohālikelike no ke ana albumin me ka bromocresol green a me ka bromocresol poni.ʻEwalukūmāiwa pākēneka (737 o 826) i loaʻa i kahi immunoglobulin (Ig)G pae o <6 g/l me ka hoʻohana ʻana i ke ʻano ʻōmaʻomaʻo bromocresol me ka ʻoki ʻia o f o <18 g/l, a he 56% (459) i loaʻa. he IgG o <4 g/l.Ua ʻike ʻia nā poʻe maʻi me ka lua a me ka mua o ka antibody deficiency a me ka serum electrophoresis a me ka immunofixation i hōʻike ʻia he 1·2% (10) i ʻike mua ʻole i nā paraproteins liʻiliʻi e pili ana me ka immune-paresis.Ke hoʻohana nei i ka poni bromocresol, 74% o nā laʻana i loaʻa ka IgG o <6 g/l me ka hoʻohana ʻana i kahi ʻoki ʻoki o <23 g/l.ʻO ka nānā ʻana me ka hoʻohana ʻana i ka globulin i helu ʻia me nā waiwai ʻoki i wehewehe ʻia e ʻike i ka hemahema o ka antibody mua a me ka lua a me nā paraproteins hou e pili ana me ka immune-paresis.He maʻalahi, loaʻa ākea a hoʻohana ʻole ʻia.Ua ʻike ʻia nā poʻe maʻi ʻaʻohe antibody me ka hoʻohana ʻana i ka ʻike mai nā helu globulin i helu ʻia, ka hoʻopōkole ʻana i ka lohi diagnostic a me ka manawa e mālama ai me ka immunoglobulin replacement therapy.